This website is written by experts in Pharmaceutical Industry Manufacturing Research and Development and Regulatory Affairs Since 2008 and in 2011 Awarded as one of top 10 websites across world in Pharmaceutical Manufacturing Regulatory
USFDA WHO GMP Guidelines Pharmaceutical Regulations Information about Pharma Quality Managment System Validations Process Validation Cleaning Validation Equipment Qualification Equipment Process Validation Computer System Validation Sterile Product Manufacturing Guidelines Media fill guideline Aseptic Techniques in Sterile dosage form Clean Room Clean Room Classification Guidelines on Area Qualification HVAC AHU HEPA Filter HEPA Filter integrity testing and leak test

Sunday, November 1, 2020

Diphenhydramine drug safety alert to stop misuse of drug

Diphenhydramine is an anticholinergic drug which is used to treat the allergy, to tam down symptoms of allergy temporarily hay fever, runny nose and sneezing.

TikTok challenge that lead to death of a youngster, was related to consuming high dosage of Benadryl,

USFDA has contacted TikToK to remove the videos related to the drug challenge, and have published about the possibility of Heart attack seizures, coma, or even death.

Therefore it is essential for patients to keep their medicines containing Diphenhydramine and combination drugs containing Diphenhydramine in lock and key and away from children.

Diphenhydramine works as anti Histaminic drug by blocking H1 receptors (Histaminic receptor) by invers agonistically blocking the effect of histamine on the body and thus protecting from allergic action of histamine.

Diphenhydramine is also used in treatment of  anaphylaxis which is a sever form of allergy which may turn in to life threatening of not treated with anti allergic drugs.

Its not only the histamine reduction but the drug blocks sodium channel by blocking the sodium ion in the sodium potassium channel of the cells, this action do affect the normal function of heart and may lead to heart problem in event of overdose.

Diphenhydramine
Diphenhydramine


No comments:

Pharma Guidelines Most Read

.

Readers Visit Number

This website is Authentic Source of Pharmaceutical Guidelines

This website is Authentic Source of Pharmaceutical Guidelines

Pharma Validations Quality Management System USFDA Guidelines WHO GMP Guidelines New Drug Update





This website consist of detail Information about Pharma Guidelines Pharma Regulatory Affairs USFDA Guidelines WHO Guidelines Pharmaceutical Quality Management System Pharma Validations Process Validation Cleaning Validation Equipment Qualification Equipment Process Validation Computer System Validation Sterile Product Manufacturing Guidelines Media fill guideline Aseptic Techniques in Sterile dosage form Clean Room Clean Room Classification Guidelines on Area Qualification HVAC AHU HEPA Filter HEPA Filter integrity testing and leak test