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Sunday, December 13, 2020

Folic acid deficiency anemia

 Folic acid deficiency anemia 

Folic acid is one of the most important vitamin for our body it is also termed as vitamin B9, folic acid is required for numerous biochemical reactions and cycles for synthesis of amino acids and thus protein synthesis, and for production of bases in our DNA, therefore deficiency of folic acid causes our blood cell to grow abnormally.
In patients with folic acid deficiency red blood cells produced are with weaker cell wall therefore the size of the RBC’S in folic acid deficient patients are larger in size than the normal. Large RBC’S stay for short life span in our body compared to normal red blood cells, they get destroyed while passing through spleen.
Therefore the patient with folic acid deficiency develop anemia , which is called as megaloblastic anemia as the Red Blood Cells are larger than the normal blood RBC’S.
There are many reasons why a person get folic acid deficiency as follows.
1.Chronic alcohol consumption
2.Tape worm infestation 
3. Celiac disease and Crohn's disease.
4.Poor diet 
5.Pregnancy associated folic acid deficiency
6.Weight loss surgeries which remove some part of intestine.
7.Over cooking food distroyes folic acid content of the food .
8.Certain drugs which are used to treat diseases like malaria and cancer 
Example of drugs which develop folic acid deficiency are as follows phenitoin, pyrimethamine, trimethoprim-sulfamethoxazole ,methotrexate, sulfasalazine, triamterene, , and barbiturates.
How to identify you have folic acid deficiency.
If some one is getting sores in mouth, over the tongue and in surrounding region in mouth regularly then this could be because of folic acid deficiency, if sores in mouth vanish after few days of treating with folic acid tablets for two to three days, then it could be an indication of folic acid deficiency which may cause anemia , women is require special attention therefore getting complete blood cell count and RBC folic acid level and hemoglobin content done will help your doctor to decide on line of treatment which will be best suitable for a patient.
Treatment for folic acid anemia:
Treatment for folic acid deficiency anemia is done basically by increasing the dietary supplement of folic acid , food rich in folic acid such as green leafy vegetables, orange, apple and citrus fruits, meat, egg ,fish, are recommended.
There tablets as well as syrups and liquids are available which are given oraly to patients until their anemic condition is completely recovered , patients with intestinal surgeries and which removed some part of intestine and patients who are suffering from Celiac disease and Crohn's disease are required to be given folic acid supplement by injection (shots) .

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