Friday, July 16, 2010

Lorcaserin a new drug proposed for weight loss drug:Developed By Arena Pharmaceuticals

New drug Lorcaserin a proposed weight loss drug:
Lorcaserin is a new drug waiting an approval from US FDA for its proposed use as a weight loss drug.
It is developed by Arena Pharmaceuticals a pharmaceutical company based in USA California .
Company is developing several drugs for treating disease like arterial thrombosis , pulmonary hypertension, arteriosclerosis, diabetes type 2 , which are currently under clinical investigations /clinical trials,
Lorcaserin is a completely new drug molecule developed by Arena , and application for approval from US FDA is filed under NEW DRUG APPLICATION (NDA) ,company has already submitted NDA for approval from US FDA.

General Name: Lorcaserin
IUPAC NAME: (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

It is a selective 5HT 2c (5-Hydroxy Tryptamin) agonist which bring about the activation of serotoninergic receptors in brain specially the 5-HT2C receptors in the hypothalamus are activated which may be responsible for weight loss .
Safety and efficacy is accessed by Arena Pharmaceuticals through sequences of clinical trials, and they have applied for this drugs approval for use as a weight loss drug.

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