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Wednesday, June 22, 2011

New biomarker identified which is linked to increased risk of kidney failure.

It will be possible to predict if a patient will get kidney failure in future and precautions can be taken to reduce the load on kidney along with hemodialysis.

It will be possible now to predict early if an patient is going to get a kidney failure in future or not, and if patient is found to be at high risk of getting kidney failure then doctors can set him on dietary control to reduce level of phosphate and dialysis and bring back health improvement which may help in controlling the worsening of the condition, this could be possible in few days from now.

As the researchers from National Institute of Diabetes and Digestive Diseases and Kidney Diseases (NIDDK) at the National Institute from health (NIH) USA University of Miami, have identified a hormone which regulates the phosphate in our body, The increased level of this hormone is associated with increased risk of getting kidney failure.
The hormone identified is called hormone fibroblast growth factor 23 (FGF23) which was found as higher as 6 times than the normal individuals , the increased level of hormone fibroblast growth factor 23 (FGF23) almost doubles the risk of kidney failure in patients with baseline glomerular filtration rate (eGFR) is 45 milliliters or higher .
Scientists are hopeful about developing a drug or a treatment for reducing the phosphate level from the gut and hormone fibroblast growth factor 23 (FGF23) which is responsible for worsening the condition in chronic kidney disease (CKD) patients.
Early earlier diagnosis of increased phosphate can be treated by controlling diet which restricts dietary intake of phosphates.
The phosphates are important building elements of our bone and are utilized to store food energy which will be utilised readily for bringing about biochemical reactions in our body and as a resources of energy rich molecules and are important constituents of nucleic acids DNA and RNA.
Increased blood phosphate level puts load on kidney and damages them over the period.a detailed out come of clinical study  is published on the NIH website.

Renin and Angiotensin System

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