Custom Search

Friday, July 13, 2012

Silky way to stabilize vaccines, antibiotics and drug molecule.

Researchers could effectively store mumps, and rubella (MMR) vaccines for 6 months at 25 Deg. Celsius, 37 Deg. Celsius, 45 Deg. Celsius, without losing potency and activity. Which otherwise requires a storage condition of 4 Deg. Celsius.

Silk film makes it possible to store vaccines, antibiotics, even at higher temperature which otherwise required cold storage conditions until it is delivered to patient.

Researchers at National institute of health USA have developed a silk-based stabilizer with which vaccines and antibiotic were successfully kept stable even at temperature 60 Deg. Celsius. The silk based stabilizer protected drug from effect of light as well. The silk based film can cover the biological active proteins and drug molecule protecting them from derivative effect of heat.

Therefore now it will be possible to keep the drug product and vaccines at room temperature which otherwise requires storage in cold condition in refrigeration, without losing potency and pharmacological activity of vaccines, antibiotics and drug molecules.

What is Cold chain Drugs and Cold chain distribution?

We all know that there are certain drugs, vaccines, and antibiotics which are required to be stored in cool condition and in refrigeration, Manufacturing and processing of these molecules require special cold conditions and intermediate stages too require cold environment even in the form of finished product until the product is delivered to patient so that they are protected from thermal degradation process, otherwise drug product or vaccine may render ineffective.

This entire process is also known as cold chain drug production and cold chain distribution, Cost of cold chain products is very higher just because of this factor, and the commercial losses due to not meeting storage in cool temperature in remote places too are higher , this is one of factor which makes vaccines costly.

With the new invention it will now be possible to design a unit dosage form in the silk based stabilizer which can hold the vaccine and antibiotics active even at temperature 60 Deg.Celcius.

The research is being carried out by Dr. Kaplan and his team from NIH's National Institute of Biomedical Imaging and Bioengineering (NIBIB) and Jeney Zhang, Ph.D. candidate, at Tufts University School of Engineering in Medford, Mass.

1 comment:

Philip Smith said...
This comment has been removed by a blog administrator.
Posted by: Martin

How to sucessfuly activate and receive our articles on pharmaceuticals by E-Mail

Dear readers if you wish to receive our articles on pharmaceutical automatically into your email Inbox , as and when we write a new article over this website, then follow these 3 simple steps.


1.You should write your Email ID in the box provided and push the subscribe butten


2.Enter the text code that we show you in a small new browser window after you enter your email ID.

3.Log in to your email and Cheke our verification email sent by "FEEDBURNER" , there you should verify the link we send you by email.




Enter your email address get our articles by email whenever this website is updated





Delivered by FeedBurner



Join the list of our readers from Universities ,Research and Development centers Pharmaceutical Companies from all over the world.











Pharma Research Regulatory Guidelines Website
Texas Dallas, TX 75211 US
Email: editor@pharmacistspharmajournal.org Website: http://pharmacistspharmajournal.org/
Copyright © 2008-2015 all rights reserve www.pharmacistspharmajournal.org